Publications

all Publications


Babski, H., Jovanic, T., Surel, C., Yoshikawa, S., Zwart, M.F., Valmier, J., Thomas, J.B., Enriquez, J., Carroll, P., Garc├Ęs, A. A GABAergic Maf-expressing interneuron subset regulates the speed of locomotion in Drosophila. (2019) Nature Communications. 10(1):4796. DOI: 10.1038/s41467-019-12693-6

+ expand abstract

Henry, L.K., Thomas, S.T., Widhalm, J.R., Lynch, J.H., Davis, T.C., Kessler, S.A., Bohlmann, J., Noel, J.P., Dudareva, N. Contribution of isopentenyl phosphate to plant terpenoid metabolism. (2018) Nature Plants. DOI: 10.1038/s41477-018-0220-z

+ expand abstract

Shen, R., Wang, B., Giribaldi, M.G., Ayres, J., Thomas, J.B., Montminy, M. Neuronal energy-sensing pathway promotes energy balance by modulating disease tolerance. (2016) Proceedings of the National Academy of Sciences of the United States of America. 113(23):E3307-14. DOI: 10.1073/pnas.1606106113

+ expand abstract

Long, H., Yoshikawa, S., Thomas, J.B. Equivalent Activities of Repulsive Axon Guidance Receptors. (2016) Journal of Neuroscience. 36(4):1140-50. DOI: 10.1523/JNEUROSCI.3406-15.2016

+ expand abstract

Yoshikawa, S., Long, H., Thomas, J.B. A subset of interneurons required for Drosophila larval locomotion. (2016) Molecular and Cellular Neurosciences. 70:22-9. DOI: 10.1016/j.mcn.2015.11.008

+ expand abstract

Read, R.D., Fenton, T.R., Gomez, G.G., Wykosky, J., Vandenberg, S.R., Babic, I., Iwanami, A., Yang, H., Cavenee, W.K., Mischel, P.S., Furnari, F.B., Thomas, J.B. A kinome-wide RNAi screen in Drosophila Glia reveals that the RIO kinases mediate cell proliferation and survival through TORC2-Akt signaling in glioblastoma. (2013) PLOS Genetics. 9(2):e1003253. DOI: 10.1371/journal.pgen.1003253

+ expand abstract

Wang, B., Moya, N., Niessen, S., Hoover, H., Mihaylova, M.M., Shaw, R.J., Yates, J.R., Fischer, W.H., Thomas, J.B., Montminy, M. A hormone-dependent module regulating energy balance. (2011) Cell. 145(4):596-606. DOI: 10.1016/j.cell.2011.04.013

+ expand abstract

Sakurai, M., Aoki, T., Yoshikawa, S., Santschi, L.A., Saito, H., Endo, K., Ishikawa, K., Kimura, K., Ito, K., Thomas, J.B., Hama, C. Differentially expressed Drl and Drl-2 play opposing roles in Wnt5 signaling during Drosophila olfactory system development. (2009) Journal of Neuroscience. 29(15):4972-80. DOI: 10.1523/JNEUROSCI.2821-08.2009

+ expand abstract

Read, R.D., Cavenee, W.K., Furnari, F.B., Thomas, J.B. A drosophila model for EGFR-Ras and PI3K-dependent human glioma. (2009) PLOS Genetics. 5(2):e1000374. DOI: 10.1371/journal.pgen.1000374

+ expand abstract

Wang, B., Goode, J., Best, J., Meltzer, J., Schilman, P.E., Chen, J., Garza, D., Thomas, J.B., Montminy, M. The insulin-regulated CREB coactivator TORC promotes stress resistance in Drosophila. (2008) Cell Metabolism. 7(5):434-44. DOI: 10.1016/j.cmet.2008.02.010

+ expand abstract

Inaki, M., Yoshikawa, S., Thomas, J.B., Aburatani, H., Nose, A. Wnt4 is a local repulsive cue that determines synaptic target specificity. (2007) Current Biology. 17(18):1574-9. DOI: 10.1016/j.cub.2007.08.013

+ expand abstract

Hughes, C.L., Thomas, J.B. A sensory feedback circuit coordinates muscle activity in Drosophila. (2007) Molecular and Cellular Neurosciences. 35(2):383-96. DOI: 10.1016/j.mcn.2007.04.001

+ expand abstract

Boyle, M., Nighorn, A., Thomas, J.B. Drosophila Eph receptor guides specific axon branches of mushroom body neurons. (2006) Development. 133(9):1845-54. DOI: 10.1242/dev.02353

+ expand abstract

Fradkin, L.G., Garriga, G., Salinas, P.C., Thomas, J.B., Yu, X., Zou, Y. Wnt signaling in neural circuit development. (2005) Journal of Neuroscience. 25(45):10376-8. DOI: 10.1523/JNEUROSCI.3429-05.2005


Labrador, J.P., O’keefe, D., Yoshikawa, S., McKinnon, R.D., Thomas, J.B., Bashaw, G.J. The homeobox transcription factor even-skipped regulates netrin-receptor expression to control dorsal motor-axon projections in Drosophila. (2005) Current Biology. 15(15):1413-9. DOI: 10.1016/j.cub.2005.06.058

+ expand abstract

Yoshikawa, S., Thomas, J.B. Secreted cell signaling molecules in axon guidance. (2004) Current Opinion in Neurobiology. 14(1):45-50. DOI: 10.1016/j.conb.2004.01.005

+ expand abstract

Imondi, R., Thomas, J.B. Neuroscience. The ups and downs of Wnt signaling. (2003) Science. 302(5652):1903-4. DOI: 10.1126/science.1092976


van Meyel, D.J., Thomas, J.B., Agulnick, A.D. Ssdp proteins bind to LIM-interacting co-factors and regulate the activity of LIM-homeodomain protein complexes in vivo. (2003) Development. 130(9):1915-25.

+ expand abstract

Yoshikawa, S., McKinnon, R.D., Kokel, M., Thomas, J.B. Wnt-mediated axon guidance via the Drosophila Derailed receptor. (2003) Nature. 422(6932):583-8. DOI: 10.1038/nature01522

+ expand abstract

Thor, S., Thomas, J.B. Motor neuron specification in worms, flies and mice: conserved and ‘lost’ mechanisms. (2002) Current Opinion in Genetics & Development. 12(5):558-64.

+ expand abstract

Diagana, T.T., Thomas, U., Prokopenko, S.N., Xiao, B., Worley, P.F., Thomas, J.B. Mutation of Drosophila homer disrupts control of locomotor activity and behavioral plasticity. (2002) Journal of Neuroscience. 22(2):428-36.

+ expand abstract

Herzig, M.C., Thor, S., Thomas, J.B., Reichert, H., Hirth, F. Expression and function of the LIM homeodomain protein Apterous during embryonic brain development of Drosophila. (2001) Dev. Genes Evol. 211(11):545-54. DOI: 10.1007/s00427-001-0195-y

+ expand abstract

O’Keefe, D.D., Thomas, J.B. Drosophila wing development in the absence of dorsal identity. (2001) Development. 128(5):703-10.

+ expand abstract

Yoshikawa, S., Bonkowsky, J.L., Kokel, M., Shyn, S., Thomas, J.B. The derailed guidance receptor does not require kinase activity in vivo. (2001) Journal of Neuroscience. 21(1):RC119.

+ expand abstract

van Meyel, D.J., O’Keefe, D.D., Thor, S., Jurata, L.W., Gill, G.N., Thomas, J.B. Chip is an essential cofactor for apterous in the regulation of axon guidance in Drosophila. (2000) Development. 127(9):1823-31.

+ expand abstract

Jurata, L.W., Thomas, J.B., Pfaff, S.L. Transcriptional mechanisms in the development of motor control. (2000) Current Opinion in Neurobiology. 10(1):72-9.

+ expand abstract

Bonkowsky, J.L., Yoshikawa, S., O’Keefe, D.D., Scully, A.L., Thomas, J.B. Axon routing across the midline controlled by the Drosophila Derailed receptor. (1999) Nature. 402(6761):540-4. DOI: 10.1038/990122

+ expand abstract

Lilly, B., O’Keefe, D.D., Thomas, J.B., Botas, J. The LIM homeodomain protein dLim1 defines a subclass of neurons within the embryonic ventral nerve cord of Drosophila. (1999) Mech. Dev. 88(2):195-205.

+ expand abstract

van Meyel, D.J., O’Keefe, D.D., Jurata, L.W., Thor, S., Gill, G.N., Thomas, J.B. Chip and apterous physically interact to form a functional complex during Drosophila development. (1999) Molecular Cell. 4(2):259-65.

+ expand abstract

Scully, A.L., McKeown, M., Thomas, J.B. Isolation and characterization of Dek, a Drosophila eph receptor protein tyrosine kinase. (1999) Molecular and Cellular Neurosciences. 13(5):337-47. DOI: 10.1006/mcne.1999.0752

+ expand abstract

Bonkowsky, J.L., Thomas, J.B. Cell-type specific modular regulation of derailed in the Drosophila nervous system. (1999) Mech. Dev. 82(1-2):181-4.

+ expand abstract

Thor, S., Andersson, S.G., Tomlinson, A., Thomas, J.B. A LIM-homeodomain combinatorial code for motor-neuron pathway selection. (1999) Nature. 397(6714):76-80. DOI: 10.1038/16275

+ expand abstract

Benveniste, R.J., Thor, S., Thomas, J.B., Taghert, P.H. Cell type-specific regulation of the Drosophila FMRF-NH2 neuropeptide gene by Apterous, a LIM homeodomain transcription factor. (1998) Development. 125(23):4757-65.

+ expand abstract

Oates, A.C., Bonkovsky, J.L., Irvine, D.V., Kelly, L.E., Thomas, J.B., Wilks, A.F. Embryonic expression and activity of doughnut, a second RYK homolog in Drosophila. (1998) Mech. Dev. 78(1-2):165-9.

+ expand abstract

Callahan, C.A., Yoshikawa, S., Thomas, J.B. Tracing axons. (1998) Current Opinion in Neurobiology. 8(5):582-6.

+ expand abstract

O’Keefe, D.D., Thor, S., Thomas, J.B. Function and specificity of LIM domains in Drosophila nervous system and wing development. (1998) Development. 125(19):3915-23.

+ expand abstract

Thomas, J.B. Axon guidance: crossing the midline. (1998) Current Biology. 8(3):R102-4.

+ expand abstract

Thor, S., Thomas, J.B. The Drosophila islet gene governs axon pathfinding and neurotransmitter identity. (1997) Neuron. 18(3):397-409.

+ expand abstract

Callahan, C.A., Bonkovsky, J.L., Scully, A.L., Thomas, J.B. derailed is required for muscle attachment site selection in Drosophila. (1996) Development. 122(9):2761-7.

+ expand abstract

Callahan, C.A., Muralidhar, M.G., Lundgren, S.E., Scully, A.L., Thomas, J.B. Control of neuronal pathway selection by a Drosophila receptor protein-tyrosine kinase family member. (1995) Nature. 376(6536):171-4. DOI: 10.1038/376171a0

+ expand abstract

Lundgren, S.E., Callahan, C.A., Thor, S., Thomas, J.B. Control of neuronal pathway selection by the Drosophila LIM homeodomain gene apterous. (1995) Development. 121(6):1769-73.

+ expand abstract

Blair, S.S., Brower, D.L., Thomas, J.B., Zavortink, M. The role of apterous in the control of dorsoventral compartmentalization and PS integrin gene expression in the developing wing of Drosophila. (1994) Development. 120(7):1805-15.

+ expand abstract

Callahan, C.A., Thomas, J.B. Tau-beta-galactosidase, an axon-targeted fusion protein. (1994) Proceedings of the National Academy of Sciences of the United States of America. 91(13):5972-6.

+ expand abstract

Muralidhar, M.G., Thomas, J.B. The Drosophila bendless gene encodes a neural protein related to ubiquitin-conjugating enzymes. (1993) Neuron. 11(2):253-66.

+ expand abstract

Muralidhar, M.G., Callahan, C.A., Thomas, J.B. Single-minded regulation of genes in the embryonic midline of the Drosophila central nervous system. (1993) Mech. Dev. 41(2-3):129-38.

+ expand abstract

Bourgouin, C., Lundgren, S.E., Thomas, J.B. Apterous is a Drosophila LIM domain gene required for the development of a subset of embryonic muscles. (1992) Neuron. 9(3):549-61.

+ expand abstract

Thomas, J.B., Crews, S.T. Molecular genetics of neuronal development in the Drosophila embryo. (1990) FASEB Journal. 4(8):2476-82.

+ expand abstract

Crews, S.T., Thomas, J.B., Goodman, C.S. The Drosophila single-minded gene encodes a nuclear protein with sequence similarity to the per gene product. (1988) Cell. 52(1):143-51.

+ expand abstract

Thomas, J.B., Crews, S.T., Goodman, C.S. Molecular genetics of the single-minded locus: a gene involved in the development of the Drosophila nervous system. (1988) Cell. 52(1):133-41.

+ expand abstract

Goodman, C.S., Bastiani, M.J., Doe, C.Q., du Lac, S., Helfand, S.L., Kuwada, J.Y., Thomas, J.B. Cell recognition during neuronal development. (1984) Science. 225(4668):1271-9.

+ expand abstract

Thomas, J.B., Bastiani, M.J., Bate, M., Goodman, C.S. From grasshopper to Drosophila: a common plan for neuronal development. (1984) Nature. 310(5974):203-7.

+ expand abstract

Thomas, J.B., Wyman, R.J. Duplicated neural structure in bithorax mutant Drosophila. (1984) Developmental Biology. 102(2):531-3.

+ expand abstract

Thomas, J.B., Wyman, R.J. Mutations altering synaptic connectivity between identified neurons in Drosophila. (1984) Journal of Neuroscience. 4(2):530-8.

+ expand abstract

Wyman, R.J., Thomas, J.B. What genes are necessary to make an identified synapse? (1983) Cold Spring Harbor Symposia on Quantitative Biology. 48 Pt 2:641-52.


Thomas, J.B., Wyman, R.J. A mutation in Drosophila alters normal connectivity between two identified neurones. (1982) Nature. 298(5875):650-1.


Wyman, R.J., Thomas, J.B. The mathematics of mosaic analysis. I: The relationship between sturts and distance. (1982) Genetics. 100(4):659-76.

+ expand abstract

Koto, M., Tanouye, M.A., Ferrus, A., Thomas, J.B., Wyman, R.J. The morphology of the cervical giant fiber neuron of Drosophila. (1981) Brain Research. 221(2):213-7.

+ expand abstract